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最新科研论文
曲显俊等(基础医学院)
PNAS --
α- fluoro-β-alanine functions as a β-ar restin1-biased ligan d
of S1PR2 to upregulate DPD expression in cancer cells
闵力等(友谊医院)
nat comm --
Multi-phase hybrid metabolomics
framework identifies clinically applicable
plasma signatures for early detection of
gastric cancer
王刚等(安定医院)
Cell Host & Microbe --
Adjunctive fecal microbiota transplantation for
major depressive disorder: Arandomized, double
blind, placebo-controlledtrial
张伟等(天坛医院)
Cancer Research --
A Deep Learning–Driven Framework Integrating
Organoid-Based Functional Validation Identifies Universal
Neoantigens from Recurrent Glioma Mutations
张晓艳等(药学院)
Biosensors and Bioelectronics --
Dual-strain engineering in Pd metallene for ultrasensitive tetracycline
electrochemical biosensing
郭强等(中医药学院)
Redox Biology --
Allosteric activation of Trx1 by antagonizing nitrative modification at
tyrosine 49 confers neuroprotection against ischemic stroke
王拥军等(天坛医院)
JAMA --
Intravenous Tenecteplase Priorto EndovascularTreatment
for Ischemic Stroke at4.5 to 24 Hours
The TNK-PLUS Randomized Clinical Trial
王伊龙等(天坛医院)
Lancet --
Ticagrelor with aspirin dual antiplatelet therapy combined
with intravenous thrombolysis in patients with ischaemic
stroke in China (TAPIS): a multicentre, double-blind,
randomised controlled trial
崔纯莹等(药学院)
Nano Today --
BBB-penetrating biomimetic nanoparticles orchestrate STING activation
and metabolic immunomodulation for potent glioma immunotherapy
冯涛/于震维等(天坛医院)
Brain --
Plasma tau-species positive neuron derived extracellular vesicles in progressive
supranuclear palsy
王伊龙等(天坛医院)
Cell --
Nanoparticles hijack calvarial immune cells for CNS
drug delivery and stroke therapy
王拥军等(天坛医院)
The Lancet --
Tenecteplase versus standard medical treatment for basilar
artery occlusion within 24 h (TRACE-5): a multicentre,
prospective, randomised, open-label, blinded-endpoint,
superiority, phase 3 trial
郝峻巍等(宣武医院)
JAMA --
Tenecteplase for Acute Non–Large Vessel Occlusion
4.5 to 24 Hours After Ischemic Stroke
The OPTION Randomized Clinical Trial
王伊龙等(天坛医院)
The Lancet --
Efficacy and safety of minocycline in patients with acute
ischaemic stroke (EMPHASIS): a multicentre, double-blind,
randomised controlled trial
王拥军等(天坛医院)
BMJ --
Edaravone dexborneol versus placebo on functional outcomes in
patients with acute ischaemic stroke undergoing endovascular
thrombectomy (TASTE-2): randomised controlled trial
李子孝等(天坛医院)
BMJ --
Effect of a clinical decision support system on stroke care quality
and outcomes in patients with acute ischaemic stroke (GOLDEN
BRIDGE II): cluster randomised clinical trial
牛晓辉等(积水潭医院)
The Lancet --
Pimicotinib versus placebo for tenosynovial giant cell
tumour (MANEUVER): an international, randomised,
placebo-controlled, phase 3 trial
洪韬/张鸿祺等(宣武医院)
Brain --
Angiogenic switching in cerebral cavernous
malformations driven by MAP3K3–PIK3CA synergy
侯胜平等(同仁医院)
npj Digital Medicine --
Apolipoprotein E drives microglia activation in the
development of autoimmune uveitis through
up-regulation of peptidyl prolyl isomerase F
王拥军等(天坛医院)
npj Digital Medicine --
Deep learning-based brain age predicts stroke recurrence in acute ischemic
cerebrovascular disease
王硕等(天坛医院)
JAMA NEUROLOGY --
Gadolinium-Enhanced Aneurysm Wall Imaging and Risk of Intracranial Aneurysm Growth or Rupture
郭力嘉/刘怡等(口腔医院)
Bioactive Materials --
Mechanism and regulatory strategy study on promoting vascularized bone
regeneration via intracellular zinc ion transport
李玉琳等(安贞医院)
Immunity --
Optogenetic vagal nerve stimulation attenuates heart
failure by limiting the generation f monocyte-derived
inflammatory CCRL2+ macrophages
邢卉春/王玺等(地坛医院)
Gut Microbes --
Gut microbial metabolite butyrate suppresses
hepatocellular carcinoma growth via CXCL11-
dependent enhancement of natural killer cell
infiltration
卢洁/唐毅等(宣武医院)
Radiology --
Modulation of Cortical and Hippocampal Functional MRI
Connectivity Following Transcranial Alternating Current
Stimulation in Mild Alzheimer Disease
金子兵等(同仁医院)
Science Bulletin --
Juvenile macular degeneration in nonhuman primates generated by
germline knockout of ABCA4 gene
王刚/闫芳等(安定医院)
npj Digital Medicine --
Randomized clinical trial of a digital
medication system to enhance adherence
in patients with severe mental disorders
孙英/王炜等(基础医学院)
Advanced Science --
Neutrophil–Endothelium Interaction Mediated by S100A9 Promotes Pulmonary Vascular Remodeling During
Pulmonary Hypertension
梁庆丰等(同仁医院)
eBioMedicine --
Bifunctional chemokine-nanobody fusion protein enhances neutrophil recruitment to impede Acanthamoeba immune
evasion
王刚/杜静等(安定医院)
npj Science of Food --
Long-term GABA supplementation
mitigates anxiety by modulating
complement and neuroinflammatory
pathways
唐毅等(宣武医院)
Science Bulletin --
Coupled sleep rhythm disruption predicts cognitive decline in
Alzheimer's disease
刘磊等(基础医学院)
Nature Communications --
A TLK2-mediated calcium-driven cell death pathway links neuronal degeneration to nuclear envelope disruption
王松灵等(基础医学院)
PNAS --
An atlas of early human mandibular endochondral
and osteogenic paracrine signaling regions of Meckel’s cartilage
王松灵等(基础医学院)
Cell Reports --
Integrated multi-omics profiling characterizes the crucial role of human dental epithelium during tooth development
闫致强等(基础医学院)
Neuron --
TMEM63B functions as a mammalian hyperosmolar
sensor for thirst
王松灵等(基础医学院)
Science Bulletin --
Nitrate ameliorates myelin loss and cognitive impairment in Alzheimer’s
disease through upregulation of neuronal sialin and subsequent
inhibition of TPPP phosphorylation
张晨/王伟/刘希成等(基础医学院)
Cell Metabolism --
Microbiota-derived lysophosphatidylcholine
alleviates Alzheimer’s disease pathology via
suppressing ferroptosis
卢洁/武力勇等(宣武医院)
Neurology --
Association of Glymphatic Function With Clinical
Characteristics in Patients With Clinical and Asymptomatic Creutzfeldt-Jakob Disease
刘静等(安贞医院)
Nature Communications --
Effectiveness of treat-to-target cholesterollowering
interventions on cardiovascular
disease and all-cause mortality risk in the
community-dwelling population: a target
trial emulation
王伟等(基础医学院)
Gut Microbes --
B. vulgatus ameliorates high-fat diet-induced obesity through modulating
intestinal serotonin synthesis and lipid absorption in mice
赵继宗/王硕等(天坛医院)
LANCET NEUROLOGY --
Safety and efficacy of early versus delayed acetylsalicylic acid
after surgery for spontaneous intracerebral haemorrhage
in China (E-start): a prospective, multicentre, open-label,
blinded-endpoint, randomised trial
李子孝等(天坛医院)
INNOVATION --
Beyond low-density lipoprotein cholesterol levels: Impact of prior statin treatment on ischemic stroke outcomes
张宏伟等(三博脑科医院)
Nature Communications --
Non-secreting IL12 expressing oncolytic
adenovirus Ad-TD-nsIL12 in recurrent highgrade glioma: a phase I trial
吴若嘉等(药学院)
Nature Communications --
Longitudinal ultra-sensitive mutation
burden sequencing for precise minimal residual disease assessment in AML
马长生等(安贞医院)
JAMA --
Pulmonary Vein Isolation With Optimized Linear Ablation vs Pulmonary Vein Isolation Alone for Persistent AF The PROMPT-AF Randomized Clinical Trial
王雅杰等(地坛医院)
Journal of Infection --
Synergistic evolution: The dynamic adaptation of SARS-CoV-2 and
human protective immunity in the real world
洪韬/张鸿祺等(宣武医院)
The American Journal of Human Genetics --
GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas
逄宇等(胸科医院)
Cell Mol Immunol --
Kynurenine-AhR reduces T-cell infiltration and induces a delayed T-cell immune response by suppressing the STAT1-CXCL9/CXCL10 axis in tuberculosis
刘亚欧等(天坛医院)
Brain --
Distinct virtual histology of grey matter atrophy in four neuroinflammatory diseases
武力勇等(宣武医院)
JAMA Neurology --
Multisite Skin Biopsies vs Cerebrospinal Fluid for Prion Seeding Activity in the Diagnosis of Prion Diseases
王刚/周佳等(安定医院)
Brain Stimulation --
Effect of add-on transcranial alternating current stimulation (tACS) in major depressive disorder: A randomized controlled trial
王刚/杨健等(安定医院)
Advanced Science --
Integrated Single-Cell RNA-seq and ATAC-seq Reveals
Heterogeneous Differentiation of CD4+ Naive T Cell
Subsets is Associated with Response to Antidepressant
Treatment in Major Depressive Disorder
冯涛等(天坛医院)
Neurology --
Distinctive Pattern of Metal Deposition in Neurologic
Wilson Disease
阴赪宏等(妇产医院)
Environmental Science & Technology --
Associations of Ambient Particulate Matter with Maternal Thyroid
Autoimmunity and Thyroid Function in Early Pregnancy
吴燕等(基础医学院)
PNAS --
Bispecific antibodies targeting two glycoproteins on SFTSV
exhibit synergistic neutralization and protection in a
mouse model
马伟等(基础医学院)
Redox Biology --
Iron accumulation in ovarian microenvironment damages the local redox
balance and oocyte quality in aging mice
冯涛等(天坛医院)
Science Advances --
Molecular beacon–based detection of circulating
microRNA-containing extracellular vesicle as an α-synucleinopathy biomarker
王伊龙/王拥军等(天坛医院)
JAMA Neurology --
Immediate- or Delayed-Intensive Statin in Acute Cerebral Ischemia The INSPIRES Randomized Clinical Trial
张建国等(天坛医院)
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY --
Contribution of basal ganglia activity to REM sleep disorder in Parkinson’s?disease
李纤/杨菲等(基础医学院)
Cell Death & Differentiation --
Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke
王伽伯等(中医药学院)
Journal of Advanced Research --
Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2
洪韬等(宣武医院)
Angiogenesis --
Somatic Braf V600E mutation in the cerebral endothelium induces brain arteriovenous malformations
李玉琳等(安贞医院)
ACS Nano --
One Endothelium-Targeted Combined Nucleic Acid Delivery System for Myocardial Infarction Therapy
冯芝恩/韩正学等(口腔医院)
Journal of Extracellular Vesicles --
The small extracellular vesicle-mediated intercellular
transformation of CXCR1Low to CXCR1High tumour cells promotes the progression of head and neck squamous cell carcinoma
马伟等(基础医学院)
Autophagy --
PLD1 promotes spindle assembly and migration
through regulating autophagy in mouse oocyte meiosis
李长龙等(基础医学院)
Gastric Cancer --
Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6
阴赪宏等(妇产医院)
Phytomedicine --
Baicalein improves the symptoms of polycystic ovary syndrome by
mitigating oxidative stress and ferroptosis in the ovary and gravid placenta
柳柯等(友谊医院)
ACS Nano --
Complete Restoration of Hearing Loss and Cochlear Synaptopathy via Minimally
Invasive, Single-Dose, and Controllable Middle Ear Delivery of Brain-Derived Neurotrophic Factor?Poly(DL-lactic acid-coglycolic
acid)-Loaded Hydrogel
贾建平等(宣武医院)
NEJM --
Biomarker Changes during 20 Years
Preceding Alzheimer’s Disease
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